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- DeepSeek’s Disruption, AI for Drug Discovery, and OpenAI Releases o3-Mini
DeepSeek’s Disruption, AI for Drug Discovery, and OpenAI Releases o3-Mini
PLUS: Build Your Own AI Chatbot and an AI-Powered Career Coach
We’re back with another issue of the latest breakthroughs, insights, and tools to keep you ahead of the curve. Whether you’re an AI engineer, business leader, developer, or creator, we’ve got everything you need to stay informed and inspired.
Here's what we're covering today:
DeepSeek shakes the AI world
Reid Hoffman’s new AI drug discovery startup
OpenAI’s o3-mini Release
How to build your own AI chatbot
Your new AI mentor in the job market
FEATURED INSIGHT💡
DeepSeek’s Open-Source Revolution Sends Nvidia Reeling

Last week, Nvidia lost $500 billion in market value—the worst loss since March 2020. The cause? DeepSeek, a Chinese AI startup shaking up the industry with an ultra-efficient open-source AI model that rivals OpenAI’s best—at just 5% of the cost.
R1, DeepSeek’s flagship model, beats OpenAI’s o1 in reasoning benchmarks and is now the #1 free app on the Apple App Store, outranking ChatGPT.
Trained for just $5.6M—a fraction of what OpenAI and Google spend on their models. (Although there is investigation ongoing into whether or not this is really true.)
Backed by private funding from founder Liang Wenfeng’s hedge fund, DeepSeek’s success is a wake-up call for AI’s future.
Why It Matters:
The Open vs. Closed Model Debate – DeepSeek’s free, open-source approach could challenge the dominance of proprietary AI.
AI’s Economic Shift – Investors are questioning whether throwing billions at AI is still viable when competitors can build something cheaper and better.
A Geopolitical Battleground? – Some hail DeepSeek’s R1 as a breakthrough; others fear it weakens U.S. AI competitiveness.
The big question: Will open-source AI dominate the future, or will Big Tech double down on proprietary solutions?
ON THE HORIZON 🌅
LinkedIn Co-Founder Takes on Cancer with AI

Reid Hoffman is teaming up with Pulitzer-winning scientist Dr. Siddhartha Mukherjee to launch Manas AI, a startup using AI to accelerate cancer drug discovery by up to 100x.
What’s New:
Generative chemistry + AI-driven molecular docking – speeds up drug design and testing.
Partnership with Microsoft – leveraging Azure cloud computing to scale drug discovery.
$24.6M in funding – backed by General Catalyst and Greylock.
Why It Matters:
AI-powered drug discovery is no longer sci-fi—it’s happening now.
Manas AI aims to replace traditional experimental methods with generative models.
The startup is initially targeting breast cancer, prostate cancer, and lymphoma, with plans to expand.
LATEST IMPORTANT NEWS 📰
OpenAI’s o3-Mini: Cheaper, Faster, and Smarter
💻 OpenAI just released o3-mini, a small yet powerful reasoning model optimized for cost and speed.
93% cheaper than OpenAI’s o1 model.
Excels in coding and problem-solving tasks.
Supports Structured Outputs, function calling, and streaming.
Best part? You can fine-tune its reasoning with three effort levels—low, medium, and high—giving you more control over performance.
FOR THE TECHNICALLY INCLINED 🛠️
Build Your Own AI Chatbot for PDF Q&A
Want to create a chatbot that can answer questions from PDFs using DeepSeek’s LLM and LangChain’s document processing? This step-by-step tutorial walks you through:
📌 How to integrate LangChain for intelligent document processing.
📌 Optimizing AI reasoning for precise Q&A interactions.
📌 Deploying a chatbot with an intuitive user interface.
🔗 Check out the tutorial: LangChain AI
AI TOOL OF THE DAY 🛠️🚀
Looking for career advice? Coach is an AI-powered career coaching platform that provides expert-backed guidance for:
✔️ Students and job-seekers – resume reviews, interview prep, career planning.
✔️ Career changers – skill-building recommendations, networking strategies.
✔️ Educators – insights into the future of work.
That's all for now!
We'll catch you in the next one.
Cheers,
The AI Horizons Team
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